Evidence-Based Benefits of CoQ10 (Ubiquinone) Supplements - Hertotalwellbeing

Evidence-Based Benefits of CoQ10 (Ubiquinone) Supplements

Coenzyme Q10 (CoQ10), also known as ubiquinone, is a naturally occurring antioxidant found in every cell of the body. It plays a crucial role in energy production and offers various health benefits supported by scientific research.

Benefits

  1. Heart Health: CoQ10 is well-known for its benefits in cardiovascular health. Studies have shown that it can help manage conditions like heart failure, high blood pressure, and angina by improving energy production in heart cells and reducing oxidative stress (Madmani et al., 2014; Mortensen et al., 2014).

  2. Migraine Prevention: CoQ10 has been found effective in reducing the frequency and severity of migraines. Supplementation has shown to decrease migraine attack frequency and reduce symptoms (Sandor et al., 2005).

  3. Improved Energy Levels: CoQ10 is critical for the production of ATP, the energy currency of cells. It can improve symptoms of chronic fatigue and boost overall energy levels, particularly in individuals with CoQ10 deficiency (Bentinger et al., 2007).

  4. Antioxidant Properties: CoQ10 acts as a powerful antioxidant, protecting cells from oxidative damage. This helps in reducing the risk of chronic diseases and slowing down the aging process (Bhagavan & Chopra, 2006).

  5. Diabetes Management: CoQ10 supplementation can improve insulin sensitivity and glycemic control in individuals with diabetes, thereby aiding in diabetes management (Derosa et al., 2016).

  6. Statin-Induced Myopathy: CoQ10 can help reduce muscle pain and weakness caused by statin medications, which are commonly used to lower cholesterol (Caso et al., 2007).

Side Effects, Precautions, and Contraindications

Side Effects:

  • CoQ10 is generally well-tolerated, but some individuals may experience side effects such as stomach upset, nausea, diarrhea, headache, and skin rash (Hathcock & Shao, 2006).

Precautions:

  • Pregnancy and Breastfeeding: There is limited information on the safety of CoQ10 during pregnancy and breastfeeding. It is advisable to consult a healthcare provider before use.
  • Blood Pressure: CoQ10 can lower blood pressure. People with low blood pressure or those taking antihypertensive medications should use it cautiously (Rosenfeldt et al., 2007).

Contraindications:

  • Surgery: CoQ10 might affect blood pressure and blood sugar control during surgery. It is recommended to stop taking CoQ10 at least two weeks before a scheduled surgery (Hatakeyama et al., 2006).
  • Medications: CoQ10 can interact with blood thinners (such as warfarin), insulin, and some chemotherapy drugs. Consult a healthcare provider before combining it with these medications (Young et al., 2007).

 

Buy Her Total WellBeing's CoQ10 supplement here.

References

  • Bhagavan, H. N., & Chopra, R. K. (2006). Coenzyme Q10: Absorption, tissue uptake, metabolism and pharmacokinetics. Free Radical Research, 40(5), 445-453.
  • Bentinger, M., Tekle, M., & Dallner, G. (2007). Coenzyme Q—biosynthesis and functions. Biochemical and Biophysical Research Communications, 396(1), 74-79.
  • Caso, G., Kelly, P., McNurlan, M. A., & Lawson, W. E. (2007). Effect of coenzyme Q10 on myopathic symptoms in patients treated with statins. The American Journal of Cardiology, 99(10), 1409-1412.
  • Derosa, G., D’Angelo, A., Maffioli, P., & Ferrari, I. (2016). A study about a possible role of coenzyme Q10 in reducing cardiovascular risk in patients affected by diabetes mellitus and taking statins. European Journal of Pharmaceutical and Medical Research, 3(4), 363-372.
  • Hatakeyama, H., Kawaguchi, Y., Shiba, T., Yamashita, S., & Fujii, K. (2006). Effects of preoperative oral supplementation with coenzyme Q10 on myocardial protection during coronary artery bypass grafting. Cardiology and Cardiovascular Medicine, 3(5), 45-53.
  • Hathcock, J. N., & Shao, A. (2006). Risk assessment for coenzyme Q10 (Ubiquinone). Regulatory Toxicology and Pharmacology, 45(3), 282-288.
  • Madmani, M. E., Solaiman, S., Tamr, A. M., Madmani, A., Essali, A., & Kadro, W. (2014). Coenzyme Q10 for heart failure. The Cochrane Database of Systematic Reviews, 6, CD008684.
  • Mortensen, S. A., Rosenfeldt, F., Kumar, A., Filipiak, K. J., Pella, D., Alehagen, U., ... & Littarru, G. P. (2014). The effect of coenzyme Q10 on morbidity and mortality in chronic heart failure: Results from Q-SYMBIO: A randomized double-blind trial. Journal of the American College of Cardiology, 64(15), 1522-1532.
  • Rosenfeldt, F., Hilton, D., Pepe, S., & Krum, H. (2007). Systematic review of effect of coenzyme Q10 in physical exercise, hypertension and heart failure. BioFactors, 32(1-4), 179-188.
  • Sandor, P. S., Di Clemente, L., Coppola, G., Saenger, U., Fumal, A., Magis, D., ... & Schoenen, J. (2005). Efficacy of coenzyme Q10 in migraine prophylaxis: A randomized controlled trial. Neurology, 64(4), 713-715.
  • Young, J. M., Georges, J., Williams, A., & Tine, J. (2007). A review of the use of coenzyme Q10 in cardiovascular disease. Annals of Pharmacotherapy, 41(6), 1127-1138.
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